NIBB-Academia Sinica International Webinar of Aquatic Model Organisms for Basic Biology to Human Disease Models

Speaker: Dr. Qiang Tu

Institute: Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China

Talk title: The multi-omics landscape of the medaka genome

Medaka (Oryzias latipes) has become an important vertebrate model widely used in genetics, developmental biology, environmental sciences, and many other fields. A high-quality genome sequence and a variety of genetic tools are available for this model organism. However, the existing genome annotation is still rudimentary; public omics datasets are limited and difficult to explore. Here we report multi-omics landscapes of medaka genome profiled by long-read RNA-seq, short-read RNA-seq, ATAC-seq, and Hi-C techniques. Integration of these datasets provides unique opportunities to understand genome activities during embryogenesis and other biological processes. We also built a user-friendly medaka omics data portal to present these datasets. This work provides a comprehensive omics data source for the medaka community and others as well.